Lack of potassium may cause muscle weakness, irregular heartbeat, mood changes, or nausea and vomiting. J Am Soc Hypertens. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight a day, taken in smaller doses during the day. N Engl J Med. June 26, 2018. Staff. Another three-month, randomized, placebo-controlled trial in 244 adults (50 years) examined the effect of oral potassium bicarbonate, at either 39 mg/kg/day or 58.5 mg/kg/day, on markers of bone turnover (29). Imran Dosani answered. 8600 Rockville Pike Low potassium concentration in blood (hypokalemia) can result in muscular paralysis or abnormal heart rhythms and can be fatal. Select one or more newsletters to continue. Potassium citrate may cause serious side effects. Because of the potential for serious side effects, one should seek medical advice before deciding to use a potassium supplement (see Safety ). 2015;30(11):2103-2111. J Physiol. Clipboard, Search History, and several other advanced features are temporarily unavailable. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. As mentioned, potassium chloride and potassium citrate treat different conditions. These pumps use ATP (energy) to pump sodium out of the cell in exchange for potassium (Figure 1). Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. In general, the daily minimum requirement for intake of potassium is 3,000 to 3,750 mg per day, or 30-40 mEq/day. Theyre odorless, and both have a salty taste. They both act as potassium supplement Read More. Since your potassium gluconate supplement contains 550mg per pill, that equates to about 8.5 tablets. However, check with your doctor or pharmacist first, since this should not be done for most tablets. Suarez M, Youssef RF. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. information and will only use or disclose that information as set forth in our notice of What is the evidence base for a potassium requirement? The National Academies of Sciences, Engineering, and Medicine. What is the difference between potassium gluconate and potassium citrate? information submitted for this request. It is used when your urine is too acidic. Thiazide treatment alone reduced serum potassium, urinary calcium and citrate without affecting urinary pH. 3. Dietary potassium intake of 4.5-5 g/day and above is typically considered safe for healthy adults as our body usually does a great job of getting rid of the excess in the urine. DOI: 10.3390/nu8070444. Portions of this document last updated: April 01, 2023. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Office of Dietary Supplements. You may not copy, modify, distribute, display, transmit, perform, publish or sell any of the copyrightable material on this website. Potassium chloride is used as a supplement to raise potassium levels in your body. Potassium citrate acts as a diuretic (making you pee more), and is used to manage, prevent or treat conditions such as: Potassium gluconate may be used to manage, prevent or treat low potassium levels (hypokalemia). In this study, the highest versus lowest quartile of urinary potassium excretion (mid-values, 3,043 mg/day versus 1,484 mg/day) was associated with a 62% lower risk of hypertension (37). (PubMed), 39. This supplement is actually a potassium salt of citric acid (occurs naturally incitrus fruits). Restricted to advanced placement science. Natural Medicines. For oral dosage form (granules for solution): Adults and teenagers20 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Lactase - Fluticasone Furoate, Vilanterol Trifenatate, Terminalia - Butabarbital, Hyoscyamine, Phenazopyridine, Healing Touch - Diphenhydramine, Zinc Oxide, Alpha-lipoic Acid - Emtricitabine, Tenofovir Alafenamide Fumarate, Parsnip - Leuprolide Acetate, Norethindrone Acetate, Tea Tree Oil - Belladonna Extract, Butabarbital Sodium. A review of CLU Working Group. ONeil C, Keast D, Fulgoni V, and Nicklas T. Food sources of energy and nutrients among adults in the US: NHANES 2003-2006. Accessed 11/19/18. Am J Clin Nutr. The main difference between potassium chloride and potassium gluconate is that one is a chloride salt and the other comes from gluconic acid. Copyright 2023 Leaf Group Ltd., all rights reserved. What Is the Difference Between Magnesium Glycinate and Magnesium Gluconate? Copyright 2023 YOUR HEALTH REMEDY. Morris RC, Jr., Schmidlin O, Tanaka M, Forman A, Frassetto L, Sebastian A. See the section on Drug interactions for a discussion of the medications that increase the risk of hyperkalemia. Hi docs, do you think it's bad to take potassium chloride with potassium citrate? Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Estimated 24-hour urinary sodium and potassium excretion in US adults. This supplement is also known as the D-gluconic acid potassium salt or potassium D-gluconate. It is sold OTC as capsules or tablets providing up to 593 mg of potassium D-gluconate, hence, containing 99 mg of elemental potassium. Linus Pauling Institute 2014(12):Cd009217. If you have kidney dysfunction, or are on certain types of medication such as potassium-sparing diuretics however, it is important to be mindful of taking in too much potassium.. National Institutes of Health, Health Claim Notification for Potassium Containing Foods. Potassium citrate and potassium gluconate While the treatment based on potassium, sodium, chloride, and magnesium supplementation in addition to other Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made. Bananas. It metabolizes quickly to reduce the acid level in urine and decrease the formation of kidney stones. For these, please consult a doctor (virtually or in person). 2018;319(12):1209-1220. (PubMed). A 2014 meta-analysis of 17 randomized controlled trials that examined the effect of the DASH diet compared to a control diet in a total of 2,561 adults found overall reductions in systolic and diastolic blood pressure by 6.7 mm Hg and 3.5 mm Hg, respectively (39). Furthermore, this mineral is an important health nutrient that is good for reducing the risk of kidney stones, lowering blood pressure, reducing the risk of stroke, and increasing bone-beneficial calcium. A study published in the Journal of the American Medical Association concluded that consuming two times more potassium than sodium in the regular diet lowers the risk of dying from heart disease considerably. Supplemental potassium can help lower blood pressure, but potassium supplements should only be used in consultation with a medical provider (see Supplements). The information on dietary factors and supplements, food, and beverages contained on this website does not cover all possible uses, actions, precautions, side effects, and interactions. We found that KCl supplementation for 4 weeks induced a significant reduction in nighttime SBP compared with placebo (116 12 vs 121 15 mm Hg, respectively, p <0.01 vs placebo), whereas KMgCit and KCit had no significant effect in the same subjects (118 11 and 119 13 mm Hg, respectively, p >0.1 vs placebo). Originally written in 2001 by: Amazon stocks potassium salt in its own brand as well as other brands. Potassium citrate is an alkalizing agent. The use of more potent potassium supplements in potassium deficiency requires close monitoring of serum potassium concentrations. Potassium Chloride contains more elemental potassium than potassium gluconate. Created for people with ongoing healthcare needs but More than half of the bodys magnesium is in the bones. Two additional meta-analyses published in 2017 also confirmed a blood pressure-lowering effect of supplemental potassium. Corticoids cause sodium retention that leads to a compensatory increase in urinary potassium excretion. Potassium is an essential mineral found in various foods. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Granchi D, Caudarella R, Ripamonti C, et al. Oregon State University, Reviewed in April 2019 by Hyperkalemia can cause nausea, slower pulse and cardiac arrest if the heartbeat gets too slow or stops. No associations were found with coronary heart disease or total cardiovascular disease. In general, the daily June 26, 2018. Before 6. Because of the potential for serious side effects, one should seek medical advice before deciding to use a potassium supplement (see Safety). This little sodium-potassium pump partially controls that energy powering your metabolism. You may opt-out of email communications at any time by clicking on Mucinex Vs. Mucinex D vs. Mucinex DM: What Is The Difference? A prolonged bout of vomiting or diarrhea can also cause hypokalemia. 307 Linus Pauling Science Center 1994;23(2):359-377. Potassium citrate supplementation decreases the biochemical markers of bone loss in a group of osteopenic women: the results of a randomized, double-blind, placebo-controlled pilot study. Abnormally elevated serum potassium concentrations are referred to as hyperkalemia. Potassium Citrate rated 8.0/10 vs Potassium Gluconate rated 0.0/10 in overall patient satisfaction.The Potassium Chloride is to increase your potassium 2017;230:127-135. What is the difference between potassium gluconate and chloride and which is better to take as an OTC supplement if one has repeated low potassium levels? A diet rich in fruit and vegetables that supplies 2.6-3.4g/day of potassium (see AI) should contribute to maintaining a low risk of chronic disease in generally healthy older adults. Your doctor may change the dose if needed. Taking potassium with meals or taking a microencapsulated form of potassium may reduce gastrointestinal side effects (50). Because many individuals in the population consume potassium in amounts that are well below the AI and because underconsumption of potassium is linked with adverse health effects, potassium has been recognized as a "nutrient of public health concern" in the 2015-2020 Dietary Guidelines for Americans. Its formula is: c6h11ko7. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Its important to follow physician recommendations, have your progress monitored and use care with dosages to avoid toxic side effects. Bottom Line Potassium Gluconate vs Potassium Chloride The main differences between the two medicines are that the KCI is given if there are low levels of both chloride and potassium in the blood, while KG is given to patients as a supplement if he has a healthy chloride level. And potassium citrate is used for certain types of kidney stones. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Staff. Effect of potassium citrate supplementation or increased fruit and vegetable intake on bone metabolism in healthy postmenopausal women: a randomized controlled trial. WebDr. Because fruit and vegetables are rich in both potassium and precursors to bicarbonate ions, increasing their consumption might help reduce the net acid content of the diet and preserve calcium in bones, which might otherwise be mobilized to maintain normal pH (see the article on Fruit and Vegetables). Descriptions. All rights reserved. Additionally, a pooled analysis of the data from all three cohorts showed that those with the highest versus lowest animal protein-to-potassium ratio were 41% more likely to develop kidney stones (21). sharing sensitive information, make sure youre on a federal 1967 Jan 16;199 (3):215-7. doi: 10.1001/jama.199.3.215. Potassium gluconate has been reported to be more palatable than potassium chloride. In: Stipanuk M, ed. However, potassium gluconate contains less elemental potassium than potassium chloride. For oral dosage form (powder for solution): Adults and teenagers15 to 25 mEq dissolved in four to six ounces of cold water, taken two or four times a day. The solution should be mixed into water or juice. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Potassium Supplement (Oral Route, Parenteral Route). Urolithiasis. Therefore, both supplements effectively treat hypokalemia and the use considers different factors. Nuts, seeds, and dairy products are also good sources of potassium. Review/update the However, most people will not take more than 100 mEq a day. Oncologist Rx'd potassium chloride capsules, 600 mg (8 MEq). (PubMed), 3. Stone M, Martyn L, and Weaver C. Potassium intake, bioavailability, hypertension, and glucose control. Your overall physical condition should determine whether you take a potassium supplement in the form of potassium gluconate or potassium citrate 3. Potential side effects of potassium citrate and potassium gluconate include: Taking a lower dose of potassium citrate or potassium gluconate can help dissipate these side effects. Bailey JL, Sands JM, Franch HA. The Linus Pauling Institute's Micronutrient Information Center provides scientific information on the health aspects of dietary factors and supplements, food, and beverages for the general public. 2018;53(5):184-195. Young DB, Lin H, McCabe RD. . Potassium bicarbonate supplementation lowers bone turnover and calcium excretion in older men and women: a randomized dose-finding trial. ) can result in muscular paralysis or abnormal heart rhythms and can be fatal, most people not. He has been reported to be more palatable than potassium chloride and potassium citrate reduce gastrointestinal effects. 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