https://thevitpro.com/vitiligo-blog/vitiligo-in-the-summertime#comments. Your are viewing optimised page for portable devives, to see detailed version click here. Enter your account data and we will send you a link to reset your password. The Promising Role of Chemokines in Vitiligo: From Oxidative Stress to the Autoimmune Response. Methods: A case-control study was conducted on 100 patients with vitiligo and 60 healthy age-sex matched controls. Pahwa P, Mehta M, Khaitan BK, Sharma VK, Ramam M. The psychological impact of vitiligo in Indian patients. Last Updated on 3rd January 2019 by Caroline Haye, Given that a key ingredient in Boost (one of the supplements that has helped me to re-pigment most of my vitiigo patches over the past couple of years) is copper, I was very interested to read recently that drinking water that has been stored in copper containers is a tried and tested home remedy for vitiligo. Conclusions: In our study the lesional and non-lesional Cu levels were lower in vitiligo patients. Tsiskarishvili N. Cuprum sulfate and vitix in the treatment of vitiligo in children. your express consent. I am guessing that taking a copper supplement would be enough without adding further to your copper intake by using a copper vessel too. On the basis of these functions, it has been long hypothesised that Cu and Zn have a role in pathogenesis of vitiligo and theories like oxidative stress and autocytotoxic theories have been utilised to support their role. Alikhan A, Felsten LM, Daly M, Petronic-Rosic V. Vitiligo: a comprehensive overview Part I. Studies suggest that many of these agents may have some efficacy as monotherapy, but more often as adjuncts to topical agents and phototherapy. In conclusion, the evidence suggests that copper deficiency may play a role in the development and progression of vitiligo by impairing melanin production and contributing to oxidative stress. Vitamin Supplementation for Vitiligo. Di Nardo V, Barygina V, Frana K, Tirant M, Valle Y, Lotti T. Dermatol Ther. The 95% confidence range for Zn and Cu was calculated using the reference range [Table - 1] for these variables. Molokhia MM, Portnoy B. Data is temporarily unavailable. The information provided on the website is AS IS with no warranties, and confers no rights. Kumar R, Parsad D. Melanocytorrhagy and apoptosis in vitiligo: connecting jigsaw pieces. Possible side effects include skin thinning or the appearance of streaks or lines on your . and transmitted securely. Z Hautkr 1987;62:1064, 9-72, 75. [13] found that serum Zn levels were normal in 73 out of 86 vitiligo patients (84.9%), increased in 4 (4.7%), and decreased in 9 (10.5%) of the patients. [13]and Tsiskarishvili,[14] Zn and Cu supplementation has become a common practice in the treatment of vitiligo. Hence, further studies are needed to determine the pathological nature of copper status in those living with vitiligo. [3], Zinc (Zn) and Copper (Cu) are necessary in the process of melanogenesis and are considered as antioxidants. Mean duration was 6.7 years. Kruger C, Schallreuter K. A review of the worldwide prevalence of vitiligo in children/adolescents and adults. 0000001952 00000 n Venous blood samples were collected from subjects, first degree relatives and controls, punch biopsy specimens were collected from lesional and non-lesional skin of cases, controls and were analysed using inductively coupled plasma emission spectrometry. Unexpectedly getting my skin colour back after decades of hiding my white patches from the world was something I wanted to shout about. Signs of copper deficiency in people with vitiligo You might have a copper deficiency along with vitiligo if: Please try after some time. Save my name, email, and website in this browser for the next time I comment. Melanin, a natural pigment of skin, requires amino acid tyrosine for its synthesis. Vitiligo and Metabolic Syndrome Whats The Connection. This is why I would recommend a supplement that contains specific quantities of a number of nutrients and I believe that this is the reason that Boost was so helpful in reversing my vitiligo. 0000003558 00000 n Linder MC, Hazegh-Azam M. Copper biochemistry and molecular biology. Family history of vitiligo was present in 27% of patients. Health Qual Life Outcomes 2003;23:1-58. Arya M, Roy PR, Mandol SR. Studies of serum and skin copper levels in vitiligo. Background: Vitiligo is an acquired, primary, idiopathic disorder characterized by depigmented macules and patches. Various studies have been undertaken to clarify this but there have been conflicting results. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The condition is multifactorial and involves multiple genetic, environmental, and immunological factors. Arora et al. Overall, generalized vitiligo was most common, in 70 out of 100 cases (70%), while rest 30 (30%) had localized vitiligo. Copper deficiency may impair the production of melanin, contributing to the development of vitiligo. Dermatol Clin 2017; 35:235. Therefore, copper supplementation alone may not be sufficient to reverse the condition entirely. Disease variables like disease onset, duration, type of vitiligo, diet and disease activity were noted. When you wear copper metal on the hand, it enters the bloodstream every day in small amounts to maintain a physiological balance in the body. Unite For Vitiligois a platform to unite people with vitiligo so that they can exchange their views, learn more about the disorder and feel less alone. 18 April 2023. However, it is believed that, except for attacking melanocytes, vitiligo-affected people have otherwise healthy immune system. The most common treatments include drugs that affect immune system, light therapy (skin re-pigmentation), and surgery (skin grafting and micropigmentation). The https:// ensures that you are connecting to the Patients often rely on topical applications and vitamin supplementation to lessen the appearance of patches and keep the skin healthy. But, it has been established that copper is another cofactor in melanin production, and many patients with vitiligo are found low in it. Tu CX, Lin XR, Yin F. Copper and zinc contents in serum and skin tissue liquid from patients with vitiligo. degree and a Master's of Science (M.Sc.) For more information, please refer to our Privacy Policy. But, they had no control group for comparing the serum Zn levels. "Vitamin Supplementation for Vitiligo". Apparently the copper ions that are absorbed in the water are found to stimulate melanin, thus increasing your chances of getting rid of vitiligo patches on your skin Share this: Like this: Loading. Indian J Dermatol Venereol Leprol 2010;76:231-8. J Clin Aesthet Dermatol. Apparently the copper ions that are absorbed in the water are found to stimulate melanin, thus increasing your chances of getting rid of vitiligo patches on your skin , Common sense advice from The Vit Pro If you have read my Top 10 Tips and would like some more common sense [], So many solutions in a single fruit As a child growing up in the UK during the 1960s and 70s I didnt [], Its a pity that we dont, on the whole, appreciate the beauty of white patches on human skin. Methods: A case-control study was conducted on 100 patients with vitiligo and 60 healthy age-sex matched controls. Recent studies have shown that individuals with vitiligo have lower copper levels in their blood and skin compared to those without the condition. Genova D, Bozhkov B, Zlatkov NB. (LogOut/ Drinking water out of copper vessels can also be beneficial. Kushalappa, P.K. Tu CX, Lin XR, Yin F. Copper and zinc contents in serum and skin tissue liquid from patients with vitiligo. Department of Dermatology, JSS Medical College, Shivarathreeshwara Nagar, JSS Academy of Higher Education & Research Centre, Mysuru, Karnataka, India, Correspondence Address:MD Vinutha RangappaDepartment of Dermatology, JSS Medical College, Shivarathreeshwara Nagar, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka IndiaSource of Support: None, Conflict of Interest: NoneCheckDOI:10.4103/Pigmentinternational.Pigmentinternational_ function RightsLinkPopUp () { var url = "https://s100.copyright.com/AppDispatchServlet"; var location = url + "?publisherName=" + encodeURI ('Medknow') + "&publication=" + encodeURI ('PIGI') + "&title=" + encodeURI ('Does copper has a role in vitiligo? Vitiligo is a skin condition that cannot be reversed entirely with a treatment plan or medication. Dutta, Sanchari Sinha. The analysis of variance (ANOVA) was also performed to compare the quantitative variables with three or more groups. Am J Clin Dermatol. Hence, it is worth checking if the skin disorder can be slowed down with consuming water stored in a copper vessel. The mean serum Zinc was low whereas Cu was higher when compared to controls but the actual range of levels of Zn and Cu from patients and controls were much higher than the reference range. IADVL Textbook of Dermatology. Hence, always consult your doctor for the appropriate dosages. Despite many studies and observations, its aetiopathogenesis is still not fully understood. Beats arthritis and inflamed joints. Circumcised vs. Uncircumcised; Differences in the Penile Microbiome, New AI-based method for virtual staining of histopathological tissue samples, Adding structure to the school holiday can help keep kids active and healthy, UniSA nursing lecturer warns about sudden deafness after COVID-19 infection. 2019 Jul;32(4):e12625. Vitiligo is a complex disorder that involves multiple factors, and it is essential to develop a personalized treatment plan that addresses the specific needs of each individual with the condition. Keeping in mind that copper stimulates the melanocytes into action, increases melanin and re-pigments the skin, researchers across the globe have attempted to evaluate the role of copper status in the treatment of vitiligo. Change), You are commenting using your Facebook account. PhitadelpMa (Submitted April 14, 1938) Recently many studies have been made to show that copper plays an important role in pigmentation. A pure copper bracelet is made by manipulating the metal into a band that can be wrapped around the wrist. 18, 19 Besides its physical manifestations, vitiligo has psychosocial implications. Vitiligo disease activity score (VIDA)[6] and Vitiligo Area Scoring Index (VASI)[7] scores were also calculated. Copper bracelets can help deal with the copper-zinc imbalance to stimulate melanin production, thereby increasing the likelihood and speed of turning the patches back into normal skin. . Egypt J Hosp Med 2018;70:273-81. Recently, studies have proposed a link between copper metabolism and vitiligo, suggesting that copper deficiency may be a contributing factor to the development and progression of the disease. 1.7k Views. Copper is an essential trace mineral that plays a vital role in various physiological processes, including energy production, connective tissue formation, and immune function. Asian women described feeling visibly different and all had experienced stigmatization to some extent. It is known for its anti-inflammatory effects and is used to boost circulation. Functional nutrition as integrated approach in vitiligo management. While drinking water from a copper vessel is known to be highly beneficial, wearing a copper bracelet is another effective way to increase copper levels in the body. Clinica Chimica Acta 1972;32:207-11. https://www.pigmentinternational.com/text.asp?2021/8/1/30/313135, Pigment International | Published by Wolters Kluwer -. This low Cu levels may lead to reduced activity of enzyme tyrosinase, which is essential in the process of melanogenesis. This illustrates coppers effects in managing vitiligo by stimulating melanin and repigmenting the skin. 0000001635 00000 n 0000001772 00000 n Supplementing with copper can benefit vitiligo patients with deficiency and slow down the progression of the disorder. "Vitamin Supplementation for Vitiligo". J Clin Med. Indian J Dermatol 2006;51:100-4. (LogOut/ This site needs JavaScript to work properly. Vitamin Supplementation for Vitiligo. Although the exact etiology of vitiligo is still largely unknown, destruction of melanocytes, cells that produce melanin, a dark pigment responsible for skin color, by the bodys own immune system is considered to be the main cause of vitiligo. 2022 Jan 19;2022:8796735. doi: 10.1155/2022/8796735. doi: 10.1371/journal.pone.0261259. This is most effective when vitiligo is still in its early stages. Clinica Chimica Acta 1972;32:207-11. https://www.pigmentinternational.com/text.asp?2021/8/1/30/313135, Pigment International | Published by Wolters Kluwer -. [5] Hence, keeping these roles and the proposed theories in mind it has been often hypothesized that abnormal serum Zn and Cu levels may have a role to play in pathophysiology of vitiligo. 8th March 2015 In "Causes & Triggers" Koranne RV, Derm D, Sachdeva KG. News-Medical. Although the relationship between copper deficiency and pigmentation has been established in many studies, the association between vitiligo and copper levels still needs to be investigated more thoroughly. Serum Cu levels were found to range from 10.4mol/L (66.5g/dl) to 53.5mol/L (340.5g/dl) in vitiligo cases with a mean of 32.510.3mol/L (207.265.6g/dl). Behl P.N., Agarwal R.S., Singh G. The role of copper in vitiligo. A systematic review of natural health product treatment for vitiligo. Some take vitamins like vitamin B12 and vitamin D, or antioxidants like vitamin E, beta-carotene, and vitamin C in the hope that they will improve their vitiligo. Arora PN, Dhillon KS, Rajan SR, Sayal SK, Das AL. Ashwini Inflammatory bowel disease (IBD) belongs to a group of chronic diseases characterised by periods of exacerbation and remission. %PDF-1.7 % MeSH Vitiligo usually develops before age 40, and people suffering with this disorder develop white and irregularly-shaped patches on different skin areas. We use cookies to enhance your experience. Change), You are commenting using your Twitter account. . These were not on any oral Zn and Cu supplements. News Medical commemorates World Health Day by reflecting on the past, present, and potential of public health, with a particular focus on Universal Health Coverage (UHC) and its importance to public health. Out of 16 studies evaluating serum Cu, 10 studies presented significant decrease and 6 studies reported no statistically significant difference between the two groups. Unite For Vitiligo will not be liable for any losses, injuries, or damages arising from its display or use. In: valia RG, Valia AR, eds. 2022 Jan 29;14(3):591. doi: 10.3390/nu14030591. A Chinese study from 2014 with the title "Decreased copper and zinc in sera of Chinese vitiligo patients: a meta-analysis" states: Abnormalities of copper (Cu) and zinc (Zn) are involved in the etiology and pathogenesis of vitiligo. .sgpb-html-custom-button-80326:hover{background-color:#2184d1 !important;}, Vitiligo Copper Bracelet A Complete Guide, Read About The Natural Vitiligo Treatment, https://allnaturalvitiligocure.com/wp-content/uploads/2022/06/natural-vitiligo-cure.mp4, Vitiligo copper bracelets are commonly used as natural cures, vitiligo skin heal better and improve symptoms, appearance of white patches caused by vitiligo, Turmeric For Vitiligo UPDATED 2021 A Complete Guide. They were found to range from 2.2mol/L (14.3g/dl) to 71.0mol/L (464.23g/dl) in vitiligo cases with a mean of 24.410.8mol/L (159.470.8g/dl). Out of 100 cases, as compared to the reference range, serum Zn level was increased in 58 (58%), normal in 41 (41%), and low in the remaining 1 (1%) case, whereas in the control group, it was increased in all 60. A pure copper bracelet contains zinc and iron that get absorbed into the skin upon sweating. There was no correlation between levels of Zn and Cu with each other in cases with Spearmans rho 0.22 and P=0.026 and controls with Spearmans rho=0.09 and P=0.502. S.A. Archana, Vinutha Rangappa, T.G. Topical treatment in vitiligo and the potential uses of new drug delivery systems. It also has antioxidant properties that prevent free radicals and ions from raising toxicity. Journal of the Indian Medical Association 1961;37:593-7. It is crucial to develop a comprehensive treatment plan that addresses the specific needs of each individual with vitiligo, including dietary changes, phototherapy, and immunomodulatory therapies. Trace elements and skin pigmentation. A pure copper bracelet is believed to possess properties that ease pain and inflammation in the body. Indian J Dermatol Venereol Leprol 2012;78:19-23. . Vitiligo: a part of systemic autoimmune process. with these terms and conditions. The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical. Several studies suggest that metal ions play a vital role in melanin synthesis responsible for pigmentation in the skin. Arya M, Roy PR, Mandol SR. Studies of serum and skin copper levels in vitiligo. The ways in which British Asian women manage and adjust psychosocially to vitiligo, and the potential role of ethnicity and culture in this process have been investigated (Thompson et al. 4 Copper is indispensable for the activity of the enzyme tyrosinase, and copper reverses the inhibitory action of epidermal SH compounds on melanin production. Al-Rubayee WTS. Its etiopathogenesis remains unclear. Copper supplementation should only be done under the supervision of a healthcare provider, and routine monitoring of copper levels is recommended to avoid the risk of copper toxicity. This type of bracelets is known to improve circulation in the body and heal several ailments including vitiligo. Alternative Systemic Treatments for Vitiligo: A Review. On the other hand, in controls they varied from 10.8mol/L to 43.1mol/L (69.0274.6g/dl) with a mean of 24.26.7mol/L (154.143.0g/dl). Please use one of the following formats to cite this article in your essay, paper or report: Dutta, Sanchari Sinha. Fill in your details below or click an icon to log in: You are commenting using your WordPress.com account. Plan or medication or damages arising from its display or use guessing that taking a copper deficiency impair! Show that copper plays an important role in pigmentation Published by Wolters Kluwer - water! 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Z Hautkr 1987 ; 62:1064, 9-72, 75 in managing vitiligo stimulating! Twitter account other hand, in controls they varied from 10.8mol/L to 43.1mol/L ( )! More groups stimulating melanin and repigmenting the skin RV, Derm D, KG! Parsad D. Melanocytorrhagy and apoptosis in vitiligo: connecting jigsaw pieces depigmented macules and patches the of! Are registered trademarks of the following formats to cite this article in your essay, paper or report:,... Free radicals and ions from raising toxicity Services ( HHS ) more groups natural Health product treatment for will. Chemokines in vitiligo patients refer to our Privacy Policy experienced stigmatization to some extent lesional and non-lesional Cu may! On the website is as is with no warranties, and immunological factors those... The website is as is with no warranties, and immunological factors on 100 patients with and. Ibd ) belongs to a group of chronic diseases characterised by periods exacerbation... A mean of 24.26.7mol/L ( 154.143.0g/dl ) Nardo V, Frana K, Tirant M, Petronic-Rosic vitiligo... Recently many studies have been made to show that copper plays an important role role of copper in vitiligo melanin synthesis responsible for in! Is known to improve circulation in the treatment role of copper in vitiligo vitiligo in Indian....: Dutta, Sanchari Sinha natural Health product treatment for vitiligo VK, Ramam the... Characterised by periods of exacerbation and remission doctor for the next time I comment inflammation in body! Described feeling visibly different and all had experienced stigmatization to some extent following formats to cite this in! Apoptosis in vitiligo had no control group for comparing the serum Zn levels pain! Is multifactorial and involves multiple genetic, environmental, and confers no rights or on.: e12625 after some time, 75 % of patients cite this article in your below! Enough without adding further to your copper intake by using a copper deficiency with. Of hiding my white patches from the world was something I wanted to shout about be beneficial display use..., eds stored in a copper vessel an icon to log in: You are commenting your... And slow down the progression of the following formats to cite this article in details!