bupropion: Wellbutrin, Wellbutrin SR, Wellbutrin XL . doxepin Surmontil (trimipramine) Sedatives Potential cannabis interaction risk: High Sedatives are not technically considered antidepressants. To prevent constipation, eat dietary fiber, drink enough water, and exercise. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. Call your doctor right away if you have a rash, itching, swelling of the face, tongue, or throat, trouble breathing, or chest pain. We comply with the HONcode standard for trustworthy health information. Learn more about Doxepin (Silenor) at EverydayHealth.com. official website and that any information you provide is encrypted Would you like email updates of new search results? If you miss a dose, take it as soon as you remember. Promethazine. Take this medication by mouth, usually once nightly within 30 minutes before bedtime on an empty stomach, or as directed by your doctor. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. 8600 Rockville Pike font-size: medium; Your doctor may adjust your dose as needed. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. 185 significant drug interactions. This medication is used to treat a certain sleep problem (insomnia). You may need to temporarily stop taking your serotonergic psychiatric medication if it becomes necessary for you to take linezolid in certain situations. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Linezolid (Zyvox) can interact with serotonergic psychiatric medications and cause serious CNS toxicity. You may continue to smoke for about 1 week after you start the medicine. . This problem can be dangerous to you or to others. If you are already taking medicine for depression or to help you stop smoking, discuss this with your doctor before taking bupropion. A brief history of the development of antidepressant drugs: from monoamines to glutamate. Drug information provided by: Merative, Micromedex. https://www.mayoclinic.org/drugs-supplements/bupropion-oral-route/precautions/drg-20062478, Advertising and sponsorship opportunities, Eating disorders (eg, anorexia, bulimia), history of or, Seizure medicine use, if stopped suddenly (eg, carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin)), or. Your list includes two medicines belonging to the 'antidepressants' category: Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Make sure you tell your doctor if you have any other medical problems, especially: There is a problem with Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. doxepin oral brand names and other generic formulations include: Adapin Oral, Silenor Oral, Sinequan Oral. WebMD does not provide medical advice, diagnosis or treatment. Unable to load your collection due to an error, Unable to load your delegates due to an error. The .gov means its official. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. You may see some benefit within a week. Portions of this document last updated: April 01, 2023. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Tips Levofloxacin (Levaquin) and ofloxacin are the most likely of the quinolone antibiotics to cause a false positive urine test for opiates. Mayo Clinic does not endorse any of the third party products and services advertised. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. This medication has been prescribed for your current condition only. The use of alcohol or other medicines that affect the CNS with bupropion may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. Click here for an email preview. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Avoid tanning booths and sunlamps. If your dose is different, do not change it unless your doctor tells you to do so. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Safety and efficacy have not been established. Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. The effects may be increased because of slower removal of the medicine from the body. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Do not stop taking this medication without consulting your doctor. nefazodone, bupropion, and mirtazapine. The antidepressants are a prototypical example of the potentially complex interactions between psychiatric medications and sleep. Combining these medications may increase the risk of seizures, which may occur rarely with either medication. Doxepin is used to treat depression and anxiety. Older adults may be more sensitive to the side effects of this drug, especially dry mouth, dizziness, drowsiness, confusion, difficulty urinating, and QT prolongation (see above). Disclaimer. This is referred to as Serotonin Syndromesigns and symptoms include mental changes (confusion, hyperactivity, memory problems), muscle twitching, excessive sweating, shivering or shaking, diarrhea, trouble with coordination, and/or fever. Some products that may interact with this drug include: cimetidine. Unauthorized use of these marks is strictly prohibited. Do not double doses. Drug Safety and Availability, Recalls, Market Withdrawals and Safety Alerts, Information about Nitrosamine Impurities in Medications, Food and Drug Administration Overdose Prevention Framework, Medication Errors Related to CDER-Regulated Drug Products, Postmarket Drug Safety Information for Patients and Providers, Risk Evaluation and Mitigation Strategies | REMS, Multistate outbreak of fungal meningitis and other infections, FDA Drug Safety Communication: Serious CNS reactions possible when linezolid (Zyvox) is given to patients taking certain psychiatric medications, FDA Drug Safety Communication issued 10-20-2011, FDA Drug Safety Communication: Updated information about the drug interaction between linezolid (Zyvox) and serotonergic psychiatric medications, FDA Drug Safety Communication: Updated information about the drug interaction between methylene blue (methylthioninium chloride) and serotonergic psychiatric medications, FDA Drug Safety Communication: Serious CNS reactions possible when methylene blue is given to patients taking certain psychiatric medications, FDA Drug Safety Podcast for Healthcare Professionals: Serious CNS reactions possible when linezolid (Zyvox, Linezolid (marketed as Zyvox) Information, Comunicado de Seguridad de Medicamentos de la FDA: Reacciones graves en el sistema nervioso central (SNC) cuando se administra linezolid (Zyvox, Amitid, Amitril, Elavil, Endep, Etrafon, Limbitrol, Triavil, Tofranil, Tofranil PM, Janimine, Pramine, Presamine, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban, Aplenzin. The results of some tests may be affected by this medicine. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. Minimally clinically significant. Please check with a physician if you have health questions or concerns. Report any new or worsening symptoms right away. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Treatment with the serotonergic psychiatric medication may be resumed 24 hours after the last dose of linezolid. J Clin Psychiatry. This medicine should come with a Medication Guide. Sleep apnea (breathing stops during sleeping), severeUse with caution. Your doctor may adjust your dose as needed. However, many patients experiencing depression are. If you are prone to frequent or excessive alcohol use, talk to your doctor before starting buPROPion. Urinary retention (trouble urinating), severeShould not be used in patients with these conditions. It is important to tell your doctor about all other medications you use, including vitamins and herbs. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. 2012;7(6):e36889. For this medicine, the following should be considered: Allergies There is 1 alcohol/food interaction with doxepin. health information, we will treat all of that information as protected health include protected health information. Dent R, Blackmore A, Peterson J, Habib R, Kay GP, Gervais A, Taylor V, Wells G. PLoS One. Use sunscreen and wear protective clothing when outdoors. . If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy. font-weight: bold; May lower seizure threshold; keep bupropion dose as low as possible. It is not known how this medication improves sleep, though it may be due to blocking histamine receptors. Promethazine is part of a group of medications called phenothiazines. Drug Interactions . Sleeping or anxiety medicine use, if stopped suddenly (eg, alprazolam (Xanax), lorazepam (Ativan), temazepam (Restoril), triazolam (Halcion))Should not be used in patients with these conditions. Avoid combinations; the risk of the interaction outweighs the benefit. sertraline, trazodone, alprazolam, escitalopram, duloxetine, Lexapro, amitriptyline, lorazepam, Zoloft, citalopram. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Do not stop taking this medicine without checking first with your doctor. If either of these effects last or get worse, tell your doctor or pharmacist promptly. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not store in the bathroom. J Clin Psychiatry. Read the Medication Guide provided by your pharmacist before you start taking doxepin and each time you get a refill. Discuss any questions or concerns about linezolid or serotonergic psychiatric medications with your healthcare professional. This survey is being conducted by the WebMD marketing sciences department. To help you remember, take it at the same time each day. Enter other medications to view a detailed report. Different brands may not work the same way. If you notice other effects not listed above, contact your doctor or pharmacist. 464 significant drug interactions. It works by increasing the amounts of certain natural substances in the brain that are needed for mental balance. doxepin oral brand names and other generic formulations include: bupropion hcl oral will increase the level or effect of doxepin oral by altering drug metabolism. Drug interactions between linezolid and selective serotonin reuptake inhibitors: case report involving sertraline and review of the literature. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. information is beneficial, we may combine your email and website usage information with This content does not have an Arabic version. Contact your healthcare professional immediately if you are taking a serotonergic psychiatric medication and develop any of the following symptoms: mental changes (confusion, hyperactivity, memory problems), muscle twitching, excessive sweating, shivering or shaking, diarrhea, trouble with coordination, and/or fever. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Liver diseaseUse with caution. Usually avoid combinations; use it only under special circumstances. If you are taking the Wellbutrin XL extended-release tablet and you miss a dose, skip the missed dose and go back to your regular dosing schedule. ChildrenUse and dose must be determined by your doctor. Do not double the dose to catch up. Talk to your pharmacist for more details. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant, Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. This medicine may cause some people to have a false sense of wellbeing, or to become drowsy, dizzy, or less alert than they are normally. What should I know regarding pregnancy, nursing and administering doxepin oral to children or the elderly. Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine only as directed by your doctor. Of the total drug interactions, At higher doses, doxepin is used to treat a variety of other conditions, including depression and other mental/mood disorders. Although not all of these side effects may occur, if they do occur they may need medical attention. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). US residents can call their local poison control center at 1-800-222-1222. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Copyright: Merative US L.P. 1973, 2023. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). [CDATA[/* >