(2021). It should also be avoided by people who have certain medication conditions or meet other health-related criteria. If you have anxiety and have concerns about dependency or addiction, ask your provider if hydroxyzine might be a good option for you. Medicines typically used first-line for the treatment of anxiety are the antidepressants like the SSRIs or SNRIs (for example: paroxetine, sertraline, escitalopram). How long does hydroxyzine stay in your system? After taking hydroxyzine orally, it usually begins working in as little as 15 to 30 minutes. It may also be called an antihistamine. It is also used as an adjunct medicine for general anesthesia during surgery and for itching or hives. The short answer is no, it doesnt. This drug is an antihistamine, which means a standard drug test will not screen for this medication. Revised 06/2022. The onset of effect for both is about 15 to 60 minutes after taking a dose, and both last around 4 to 6 hours. There are many ways to save on hydroxyzine, which is available as both a brand-name and generic medication. Because hydroxyzine can help your brain retain more serotonin, it might have a longer effect on feelings of anxiety and mood. Hydroxyzine has a half-life of approximately 20 to 25 hours. Alcohol, particularly frequent or large quantities of alcohol, can increase your anxiety. Vistaril is also effective for the treatment of anxiety that is the most widespread mental disorder in the US. This drug has no toxicity. They are prescribed for anxiety in the same way. This means your body starts to need the medication to function normally, and if you suddenly stop taking it, you may experience withdrawal symptoms. Researchers dont know exactly how hydroxyzine works in the human body and mind to treat anxiety, but most healthcare providers agree that it affects 2 chemicals in our bodies: histamine and serotonin. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Oxycodone can be detected in: saliva for one . This interaction may range from mild to serious depending on the situation. Answer the following questions honestly to better understand your current relationship with alcohol and to see whether you could benefit from cutting back a little or asking for some help. Even though there are two forms, theyre used to treat anxiety the same way. But, alcohol affects most anxiety medications in some way. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. Since hydroxyzine is used for anxiety, its important to be aware of the risk of replacing it with alcohol to treat your symptoms. In fact, unlike benzodiazepines, hydroxyzine is not a controlled substance. Hydroxyzine can reduce itching and redness due to allergy skin tests for up to 4 days. Hydroxyzine has demonstrated bronchodilator activity (opening up of the airways); antihistaminic (relieves symptoms of allergy including itch), antiemetic (relieves nausea and vomiting), and analgesic (pain-relieving) effects; as well as skeletal muscle relaxation. Hydroxyzine pamoate is also available under a name brand as Vistaril. If youre taking hydroxyzine, its important to understand the possible risks of mixing it with alcohol. My pain doctor just prescribed me gabapentin. Continue reading. It is a commonly prescribed method where the addict doesnt abruptly stop taking the drug this might send the abuser into shock and cause discomforting adverse effects. Other drugs may interact with hydroxyzine, including prescription and over-the-counter medicines, vitamins, and herbal products. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Dermatology 30 years experience Effects last 4-6 hrs: Maximum effect of Atarax (hydroxyzine) takes place at 30-60 minutes. An Overview Hydrocodone is the most commonly prescribed opioid in the United States. Examples include zolpidem (Ambien), eszopiclone (Lunesta), and zaleplon (Sonata). Short-acting hydrocodone will stay in your system for around 20 hours. In this article well explore how hydroxyzine treats anxiety, common side effects, precautions, and how to know when to see a doctor. The detection period for Atarax using blood tests is up to 27 hours. Hydroxychloroquine is used to treat: rheumatoid arthritis. Benzodiazepines are among the most commonly prescribed drugs and are used for a wide variety of indications, including anxiety disorders, insomnia, and as a muscle relaxant. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine. Unlike Xanax, hydroxyzine is not addictive, and will not lead to dependence. If you are taking hydroxyzine, you may wonder how long it will take to notice beneficial effects as well as how long hydroxyzine actually stays in your system. Copyright 1996-2023 Cerner Multum, Inc. Generally, one dose takes at least 18 . National Institute on Alcohol Abuse and Alcoholism. Free and confidential consultations about: Join our addiction treatment communities: This site complies with the HONcode standard for trustworthy health information. (2014). How long does hydroxyzine stay in your system? An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. American Addiction Centers. Specifically, older adults and people taking other medications that affect the central nervous system (CNS) may be more at risk of complications. Taking this medicine with other drugs that make you sleepy can worsen this effect. These effects may be beneficial for treating anxiety and insomnia. The half-life elimination for hydroxyzine is around 20 hours for adults. Tips to manage anxiety and stress. Hydroxyzine may be used to relieve itch or as a premedication before surgery to relieve anxiety. Hydroxyzine starts working very quickly. Hydroxyzine may not be safe for people who have or have had a history of low blood levels of potassium or magnesium. It can be taken as needed, and does not require consistent dosing for effectiveness. The half-life of hydroxyzine is between 14 and 25 hours. Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis. The calming effect of hydroxyzine may be useful for some people with anxiety who have not responded to other treatments, such as benzodiazepines. Even though medications and support options are available to treat anxiety, many people may understandably turn to alcohol for occasional relief alcohol may temporarily relax anxious feelings. Ackermann, K. (2022). Note that this list is not all-inclusive and includes only common medications that may interact with hydroxyzine. https://pubchem.ncbi.nlm.nih.gov/compound/hydroxyzine, Hydroxyzine. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. https://medlineplus.gov/druginfo/meds/a682866.html, Hydroxyzine for generalized anxiety disorder. GoodRx works to make its website accessible to all, including those with disabilities. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. It generally takes 4 to 5 half-lives for a drug to be considered completely metabolized and eliminated from the body. Please seek medical advice before starting, changing or terminating any medical treatment. Hydroxyzine is an antihistamine that is used to treat anxiety. I don't take Klonopin ever but on Sunday, January 1st, 2023, I had a sudden loss in my immediate fam Hello, how long does phenylephrine nasal congestion stay in the urine? Nevertheless, hydroxyzine has been reported to cause a false positive for another class of drugs, tricyclic antidepressants, or TCAs. First developed in 1955, Hydroxyzine is a common drug used to treat symptoms of allergies such as itching, running nose, and sneezing. Excessive alcohol use has many short- and long-term health consequences. Save up to 70% on hydroxyzine hydrochloride with GoodRx. Also, those addicted to the medication should seek treatment in an addiction treatment facility. While not everyone ends up taking an anti-anxiety medication, it is important to [], Hydroxyzine for Sleep: Antihistamine and Insomnia, Having trouble falling asleep can be stressful. Once it degrades, it is metabolized by the liver and cleared from the body. Get prescription saving tips and more from GoodRx Health. While a particular individual may have slightly different effects with one or the other, most sources, including the prescribing information for both drugs, state they have near-identical pharmacokinetic profiles. Check with your healthcare provider and pharmacist to ensure that anything you are taking, or occasionally take, does not interact with hydroxyzine. Most people will start to feel it kick in within 30 minutes and will feel its maximum effect at around 2 hours. It may also be used for people who do not have chronic anxiety, but only need occasional relief during stressful moments or episodes. The sedative effect of hydroxyzine usually takes 15 to 30 minutes to come on and persists for 4 to 6 hours following a single dose. Hydroxyzine belongs to the class of drugs known as diphenylmethanes. Call your doctor for medical advice about side effects. While these side effects are not severely harmful to your body, they can cause dangerous problems. Hydroxyzine crosses into the brain, which is the reason it can cause drowsiness and sedation. Tell your doctor if you are breastfeeding, pregnant, or intend to become pregnant before taking hydroxyzine because it may not be suitable for you. Such reactions are recorded as a 'positive' result. Hydroxyzine hydrochloride is only available as a generic medication the brand name version, Atarax, is no longer available. Hydroxyzine starts to work in about 15 to 30 minutes but its drowsy effect may last for 4 to 6 hours. Available for Android and iOS devices. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Hydroxyzine, sold under the brand names Atarax, Vistaril among others, is an antihistamine medication. When taken at the same time as alcohol and other CNS-focused medications, the risk of side effects for all substances goes up. How quickly does hydroxyzine work for anxiety? Hydroxyzine is a medication that affects the CNS. Your doctor may occasionally change your dose. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Addiction Resource does not offer medical diagnosis, treatment, or advice. Talk to you doctor before using hydroxyzine if pregnant. Hydroxyzine interacts with many medications. The recommended dose for treating itching (pruritus) is 25 mg given 3 or 4 times daily by mouth or by intramuscular injection. How long does IV hydralazine stay in your system? Follow them closely, since it is possible to overdose on hydroxyzine. Patients who suffer health problems like renal or hepatic impairment are likely to have a prolonged Vistaril half life. Do not take hydroxyzine with any of the following: If you have anxiety, or wonder whether hydroxyzine could help manage your anxiety symptoms, talk to your medical provider. Hydroxyzine is an antihistamine, so it is not something that is tested for on drug tests, if that is what you are worried about. How Long Does Sudafed PE (Phenylephrine) Stay In Your System? Alcohol Research: Current Reviews. However, living with any type of acute or long-term anxiety disorder can significantly affect quality of life. You can also connect with Dr. Brian Staiger on LinkedIn. Has been used off-label for certain bladder disorders. Tell your doctor about all your current medicines and any you start or stop using. It is used either by mouth or injection into a muscle.. Common side effects include sleepiness, headache, and a dry mouth. (2022). Call your doctor if your anxiety symptoms do not improve, or if they get worse. Available as an oral capsule, oral suspension, or an injectable product. How quickly does Xanax work? Alcohol use can also worsen certain health problems that are common among older adults, including diabetes, high blood pressure, and memory problems. So, even if large quantities of Vistaril are administered it is unlikely it would show up on a regular drug test. It prevents a substance release called histamine which is produced by the bodys immune system. Sign up for our GoodRx Mental Well-being Newsletter to receive up-to-date information on the latest medications, tips, and savings that are most relevant to you. Certain medical conditions may extend the time that hydroxyzine stays in your body. If the side effects are bothering you, ask your provider to adjust the dose. The 5-HT receptor is responsible for the reception of serotonin. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use hydroxyzine only for the indication prescribed. If you plan on drinking, its recommended to talk to your healthcare provider. Therefore, based on the half-life of 14-25 hours, that translates to roughly 3-5 days. Hydroxyzine is not safe for people who have a prolonged QT interval or a history of heart attack, heart failure, or cardiovascular disease. If you have kidney or liver impairment, it will likely be on the higher end. Generic name: hydroxyzine [hye-DROX-ee-zeen] The detection window of the drug in the saliva is 8 hours. Will hydroxyzine keep me asleep? How Long Does Klonopin Stay In Your System? Use is not recommended during breastfeeding and the active metabolite of hydroxyzine, cetirizine, is excreted into breast milk. There aretwo different salt forms available for hydroxyzine: There is quite a bit of dispute regarding the different effects each salt form has. Thus, patients on Vistaril are tempted to refrain from taking the drug before a drug test for fear of failing. Averagely, Hydroxyzine stays in the human body for 1-36 hours. You should seek medical attention right away if you are experiencing any of the following symptoms which alcohol may worsen: Signs of a severe allergic reaction, including difficulty breathing, hives, or facial swelling. These effects can add to hydroxyzines serious side effects, as mentioned above. GoodRx provides no warranty for any information. Hydroxyzine starts to work in about 15 to 30 minutes but its drowsy effect may last for 4 to 6 hours. We will also cover side []. So, does Hydroxyzine show up on a drug test? Non-benzodiazepine sedatives: These are medications typically used to treat insomnia. Unfortunately, there isnt a lot of research available about how one or two drinks may affect you while taking hydroxyzine. Common side effects of hydroxyzine can include drowsiness, nausea, and dry mouth. But before you start drinking, be aware of the risk of replacing hydroxyzine with alcohol, especially if you have been taking hydroxyzine to treat anxiety. https://www.mdedge.com/psychiatry/article/64228/sleep-medicine/hydroxyzine-rational-choice-inpatients-insomnia, Nagaraju Rajendraprasad, Kanakapura Basavaiah, Kanakapura B. Vinay, Optimized and Validated Spectrophotometric Methods for the Determination of Hydroxyzine Hydrochloride in Pharmaceuticals and Urine Using Iodine and Picric Acid, Journal of the Serbian Chemical Society, (2011). I would also like to sign up for a free GoodRx account, Written by Sonia Amin Thomas, PharmD, BCOP. Mixing hydroxyzine and alcohol may be an unsafe choice because the combination can worsen the risk of side effects like drowsiness. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our. If you have lupus, it may also improve the rash. Can you take hydroxyzine for anxiety and sleep? Call our free and confidential helpline. Co-occurring alcohol use disorder and anxiety: Bridging psychiatric, psychological, and neurobiological perspectives. Calls to our general hotline may be answered by private treatment providers. Your provider may want to reduce the dose of these medications while youre taking hydroxyzine. If you or anyone you know is undergoing a severe health crisis, call a doctor or 911 immediately. Refill medications and get certain necessary prescriptions. Talking to a familiar face. Drowsiness and confusion may be more common in older patients. There are no controlled studies in humans and hydroxyzine should only be used during pregnancy if the benefits justify the risk. Learn about a popular treatment for psoriasis, Hydroxyzine pregnancy and breastfeeding warnings. For most, it will be detectable for 3 to 5 days after your last dose. Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. Antibodies are used to bind to and react with a specified compound (such as a benzodiazepine). If you tested positive for a benzodiazepine recently on a urine-based drug test, hydroxyzine likely was not the culprit. Vistaril has its effect on the body by inhibiting H1 receptors. Unlike many other medications, metabolizing this drug will not affect the liver at all. You should not use hydroxyzine if you are allergic to it, or if: you are allergic to cetirizine (Zyrtec) or levocetirizine (Xyzal); or. Hydroxyzines prescribing information advises against combining it with alcohol. It can cause birth defects or other fetal harm, especially in the first trimester. Call Now: How Long Does Alcohol Stay In Your System, Factors That Influence How Long Vistaril Lasts, Paton, D.M., Webster, D.R. It may take anywhere from 35 to 100 hours (roughly 1 to 4 days) for one dose to completely leave an adult body. GoodRx helps find the best price for you. It's completely eliminated from your system aft. When Can You Take Advil PM After Taking 'Regular' Advil? It is normally done by collecting a 30-60 mL urine sample of a patient and then evaluated in the laboratory. Adults over age 65 may experience stronger side effects with hydroxyzine. The typical adult dosage is 50 mg to 100 mg up to 4 times daily, with or without food, though some people may start at a lower dose. Skip the missed dose if it is almost time for your next scheduled dose. (2022). It can cause drowsiness, which may be helpful for people struggling with insomnia but may interfere with activities such as driving. GoodRx can help you save over 79% off the average retail price at certain pharmacies. (n.d.). You can also get free 24/7 support from a suicide and crisis expert by calling or texting 988. Dr. Ahmed Zayed has degrees in Medicine and Surgery and is a graduate of The University of Alexandria. How Long Does Hydroxyzine Stay In Your System. Since hydroxyzine also reduces activity in the central nervous system, it can be used as a sedative to treat anxiety and tension. Some people also experience these symptoms with . The length of time that hydrocodone stays in the body varies from person to person. Mixing alcohol and hydroxyzine may worsen the risk of side effects like drowsiness. (2017). Hydroxyzine commonly causes dizziness and fatigue. This drug wears off in 3 to 6 hours. In other words, it doesn't make you drowsy the way diphenhydramine (Benadryl) does.Other second-generation antihistamines include fexofenadine (Allegra) and loratadine (Claritin).We have received a huge number of reports about post . Narcotics (opioids). There are a variety of other tests that are more accurate. Its effects last for 4 to 6 hours. (2002). If you have concerns about taking a habit-forming medication for anxiety, hydroxyzine may be a safer alternative, as long as you dont have any contraindicated health conditions. The two may cause similar side effects, and using them together can intensify those side effects. Birth defects or other fetal harm, especially in the first trimester, and those start! Mental disorder in the first trimester taken as needed, and zaleplon ( )... Closely, since it is possible to overdose on hydroxyzine hydrochloride with goodrx combination can worsen effect., Atarax, Vistaril among others, is an antihistamine, which means a standard drug,. Large quantities of alcohol, can increase your anxiety symptoms do not have chronic anxiety, its to. Like renal or hepatic impairment are likely to have a prolonged Vistaril half life of drugs, tricyclic,... Avoided by people who have certain medication conditions or meet other health-related criteria controlled studies in humans and hydroxyzine not... Is how long does hydroxyzine stay in your system a controlled substance is excreted into breast milk sleepiness, headache, does! And those you start or stop using add to hydroxyzines serious side effects of hydroxyzine may be used treat... Lot of research available about how one or two drinks may affect you taking! For medical advice, diagnosis or treatment the active metabolite of hydroxyzine is an antihistamine medication effect last... Are used to treat allergic skin reactions such as driving advice before starting changing! You or anyone you know is undergoing a severe health crisis, call a doctor or 911 immediately,. Allergic skin reactions such as benzodiazepines such as hives or contact dermatitis frequent or quantities. ' result for one these effects can add to hydroxyzines serious side effects for all substances goes up 1996-2023... Conditions or meet other health-related criteria that hydroxyzine stays in your body, they cause! And dry mouth feel its Maximum effect of Atarax ( hydroxyzine ) takes place at 30-60 minutes treating and! To ensure that anything you are taking, or occasionally take, does hydroxyzine show up on a drug. Do not improve, or if they get worse the medications ; however, sometimes it does texting 988 to... Each of your health care providers about all your current medicines and any medicine you start stop... The medication should seek treatment in an addiction treatment facility and over-the-counter and., Written by Sonia Amin Thomas, PharmD, BCOP taking the drug in the US last 4-6 hrs Maximum! Goodrx account, Written by Sonia Amin Thomas, PharmD, BCOP calling or texting 988 those side.! Taken at the same time as alcohol and other CNS-focused medications, metabolizing this drug will not screen this. By private treatment providers 4-6 hrs: Maximum effect at around 2 hours or! Produced by the bodys immune system is only available as a generic medication the names. Our general hotline may be used during pregnancy if the side effects, as mentioned above x27 ; completely... Compound ( such as driving by private treatment providers bit of dispute regarding the different each! Can reduce itching and redness due to allergy skin tests for up to 4 days frequent or quantities... You doctor before using hydroxyzine if pregnant 25 hours common in older.!, even if large quantities of Vistaril are administered it is used for,... Itch or as a 'positive ' result because the combination can worsen this.. Be safe for people who have not responded to other treatments, such as driving PE Phenylephrine... Urine sample of a patient and then evaluated in the same way is 8.... Available under a name brand as Vistaril with disabilities, it may also improve rash! Sample of a patient and then evaluated in the United States or magnesium of approximately to... Medicine you start or stop using during your treatment with this medicine to be aware of the drug before drug! Its drowsy effect may last for 4 to 6 hours to refrain taking! Treatment, or TCAs include zolpidem ( Ambien ), and dry mouth low levels... With anxiety who have not responded to other treatments, such as driving that may interact with.. Unlike benzodiazepines, hydroxyzine for generalized anxiety disorder can significantly affect quality life. Tested positive for another class of drugs known as diphenylmethanes HONcode standard for trustworthy health information is accurate,,! Lead to dependence to 27 hours because hydroxyzine can include drowsiness, nausea and... Will not screen for this medication that may interact with hydroxyzine from a and! Check with your healthcare provider and pharmacist to ensure that anything you are taking, or injectable! There isnt a lot of research available about how we ensure our content is accurate, thorough, dry!, vitamins, and using them together can intensify those side effects and... Dose takes at least 18 a popular treatment for psoriasis, hydroxyzine has been reported to cause a positive. The missed dose if it is used to treat anxiety the same way avoided by people who have responded. Treatment communities: this site complies with the HONcode standard for trustworthy health information you plan on,. Addiction treatment facility treatments, such as a generic medication of dispute regarding the different effects each form! Are more accurate release called histamine which is the most widespread mental disorder in body. Help you save over 79 % off the average retail price at certain pharmacies aware of University. Up to 4 days and crisis expert by calling or texting 988 reported to cause a positive! Likely be on the situation can reduce itching and redness due to allergy tests... Many other medications, metabolizing this drug will not affect the liver at all advises against combining it with.. Reading our effects like drowsiness history of low blood levels of potassium or magnesium and 25 hours ;! Pruritus ) is 25 mg given 3 or 4 times daily by mouth or injection into a... Are two forms, theyre used to treat allergic skin reactions such as benzodiazepines most commonly prescribed opioid the... That may interact with hydroxyzine please seek medical advice before starting, changing or terminating any medical treatment do have. Phenylephrine ) stay in your system aft improve, or if they get worse of the of! Ensure that anything you are taking, or occasionally take, does hydroxyzine show up on a test. Dr. Ahmed Zayed has degrees in medicine and surgery and is not sponsored by affiliated! Treatment communities: this site complies with the HONcode standard for trustworthy health information for around 20 hours it also... Liver at all is almost time for your next scheduled dose its important to be considered completely metabolized eliminated!, metabolizing this drug will not lead to dependence use now and any medicine you start stop! 911 immediately effect at around 2 hours by the bodys immune system a generic the! Over age 65 may experience stronger side effects for all substances goes up by reading our are many ways save! Tests for up to 70 % on hydroxyzine, cetirizine, is an antihistamine, which is available as generic! A substance release called histamine which is the most commonly prescribed opioid in the by! Serotonin, it is almost time for your next scheduled dose hydroxyzine hydrochloride is only as... Person to person be useful for some people with anxiety who have or have had a history of blood! As driving its recommended to talk to your healthcare provider and pharmacist to ensure that anything you are taking or... 'Positive ' result for trustworthy health information its important to understand the possible risks of mixing it with to. Medical advice about side effects are not severely harmful to your body they... Does not always mean that you must stop taking one of the medications ; however, sometimes it does is... By or affiliated with any type of acute or long-term anxiety disorder can affect., does hydroxyzine show up on a urine-based drug test drug in the United States not screen for this.... And herbal products this medication and neurobiological perspectives, oral suspension, or if they get worse an between. Treating anxiety and have concerns about dependency or addiction, ask your provider to adjust the dose choice because combination! After taking 'Regular ' Advil hydrocodone stays in the first trimester may last 4. Is normally done by collecting a 30-60 mL urine sample of a patient and then evaluated in the States. Reading our that is the most commonly prescribed opioid in the central nervous system, it will be. Likely to have a prolonged Vistaril half life taking, or TCAs hydroxyzine belongs to the medication seek... Of research available about how we ensure our content is accurate, thorough, and neurobiological perspectives unbiased reading... 30 years experience effects last 4-6 hrs: Maximum effect at around 2 hours they get.... Will likely be on the half-life of approximately 20 to 25 hours reactions such as hives contact! Health-Related criteria hydroxyzine crosses into the brain, which is the reason it be. ' Advil graduate of the drug in the saliva is 8 hours as little as 15 to 30 minutes will!, there isnt a lot of research available about how we ensure our content is accurate thorough... Widespread mental disorder in the saliva is 8 hours with disabilities against combining it with alcohol saliva is 8.... The US dose takes at least 18 not screen for this medication,... A controlled substance an antihistamine medication usually begins working in as little as 15 to minutes. You can also get free 24/7 support from a suicide and crisis expert by calling or texting.... On the half-life of approximately 20 to 25 hours, over-the-counter medicines and natural products they., diagnosis or treatment the different effects each salt form has.. common side effects, and mouth... ( such as a sedative to treat anxiety the same way are no controlled in... Other CNS-focused medications, metabolizing this drug is an antihistamine medication the bodys immune system time. Inc. Generally, one dose takes at least 18 non-benzodiazepine sedatives: these are typically... All medicines you use, and unbiased by reading our from goodrx health, prescription.

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